26-66 DYNAMIC LIGHT SCATTERING INSTRUMENT FOR TURBID SAMPLES

The instrument should be capable of strongly suppressing the contribution of multiple light scattering and should allow reliable DLS measurements using very small sample volumes, including highly valuable or limited-availability samples. Technical specifications • Compact benchtop design: The instrument must be suitable for installation on a standard laboratory bench, with a maximum footprint of 50 cm × 60 cm. The instrument must be fully enclosed and compliant with the requirements for a Class 1 laser product during normal operation. • Low sample volume: The instrument must allow measurements using a total sample volume of less than 10 µL. • Multiple-scattering suppression: The instrument must provide efficient suppression of multiple light scattering, allowing DLS measurements on turbid and strongly scattering samples without requiring dilution. The preferred technology is 3D cross-correlation or an equivalent technology based on the discrimination of single- and multiple-scattering contributions. • Particle-size range: The instrument must be capable of measuring hydrodynamic particle sizes in the range of at least 1–5000 nm. • Temperature control: The instrument must provide controlled sample-temperature measurements over a range of at least 5–80 °C. • Measurement reliability for turbid samples: The supplier should provide quantitative information demonstrating the performance of the multiple-scattering suppression technology, including the maximum sample turbidity or optical density for which reliable particle-size measurements can be obtained User Friendly Software: The instrument must be supplied with control software that enables users to define measurement procedures and protocols, as well as to visualize and analyze measurement results. The software should provide an intuitive interface for non-expert users while offering expert users detailed control over experimental parameters and data analysis routines.